![]() Worldwide, GE Healthcare employees are committed to serving healthcare professionals and their patients in more than 100 countries. Headquartered in the United Kingdom, GE Healthcare is a unit of General Electric Company (NYSE: GE). Our "healthymagination" vision for the future invites the world to join us on our journey as we continuously develop innovations focused on reducing costs, increasing access and improving quality around the world. In addition, we partner with healthcare leaders, striving to leverage the global policy change necessary to implement a successful shift to sustainable healthcare systems. Our broad expertise in medical imaging and information technologies, medical diagnostics, patient monitoring systems, drug discovery, biopharmaceutical manufacturing technologies, performance improvement and performance solutions services help our customers to deliver better care to more people around the world at a lower cost. GE Healthcare provides transformational medical technologies and services that are shaping a new age of patient care. As part of the GE Healthcare BioProcess™ media platform, Capto ImpRes ion exchangers are manufactured under validated production methods, backed up with Regulatory Support Files, and have Secure Supply routines in place. device and its equivalent column (media: Capto Q anion exchange, bed volume: 5 mL. "Capto ImpRes media have been designed to meet the throughput and high resolution needs of intermediate purification and polishing."Ĭapto ImpRes media are available in several convenient formats, including Predictor™ 96-well filter plates and prepacked HiTrap™ and HiScreen™ columns to support all stages of biopharmaceutical development and manufacture. Conclusions Preparative columns used in large-scale biopharmaceutical. "The extension of the Capto platform with Capto ImpRes ion exchangers demonstrates our commitment to supporting biopharmaceutical manufacturers with the most modern tools to improve their processes in terms of throughput, productivity, and economy," said Dr Nigel Darby, Vice President, Biotechnologies, GE Healthcare. In addition, the residence time was varied from 2 to 8 min. Based on the results for SBC, binding pH was varied between pH 6.0 and 7.84 and salt concentration from 0 to 200 mM NaCl. ![]() Virus removal from antibody solutions was also achieved using CEC columns packed with beads of Capto S 202 and SP Seph FF resin 203. The first Capto ImpRes products to be launched are Capto SP ImpRes and Capto Q ImpRes, strong cation and strong anion exchangers, respectively, that enable high throughput, high resolution polishing, and flexibility in process design.Ĭapto ImpRes media are based on a rigid high-flow agarose matrix that allows the use of high flow rates and higher bed heights, providing biopharmaceutical manufacturers with the possibility to reduce cycle times and maintain or reduce column equipment footprint, thus contributing to driving improvements in process economics. The influence of pH and salt concentration on DBC was measured by DoE using Capto adhere ImpRes packed in a Tricorn 5/50 column. Thus, Capto Q AEC was associated with CC700 MMC in a two-step flow-through process to purify cell-based influenza viruses for vaccine manufacturing. I am currently diluting my samples in Buffer A (100 mm of. Uppsala, Sweden – GE Healthcare, a unit of General Electric Company (NYSE: GE), announced today that the capabilities of the well-established Capto platform are now extended to include Capto ImpRes ion exchange chromatography media for late-stage purification of a wide range of biomolecules. Can anyone help with a Capto Q column I have a protein which PI is 1.8 and I am having lots of trouble to bind it to a Capto Q column.
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